Type 2 diabetes is a rising global health burden, which is a multifactorial, heterogeneous group of metabolic disorder with the common feature characterized by a deficienc\ or failure in maintaining normal glucose homeostasis; this is due to defective insulin secretion, resistance insulin action or due to a combination of both. Diabetes mellitus is a serious condition with potentially stressful complications that aوٴects all age groups worldwide. Нe American Diabetes Association (ADA) divides diabetes mellitus into four categories. Type 2 diabetes mellitus (T2DM) is the second category and most diabetes is sorted in this category, a heterogeneous group of disorders caused by some combination of insulin resistance and impairment of insulin secretion. Insulin resistance is a condition in which the body’s muscle, fat and liver cells does not use insulin eوٴectivel\ leads to high concentration of glucose in the circulation and occurred when the body can no longer produce enough insulin to compensate for the impaired ability to use insulin.