Gastric Neuroendocrine Carcinoma

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Gastric and oesophageal neuroendocrine carcinomas are not common tumours. They occur most commonly in men in their 50s1). Risk factors of their occurrence are unknown. The site of occurrence is most common in the middle oesophagus or body of the stomach and their localization is diagnosed by endoscopy, but their gross morphology is like more common types of cancer. It is important in differential diagnosis to depend on pathological findings. Developmental forms of neuroendocrine carcinoma are like normal types of cancer. Lymph node metastasis is common at the time of diagnosis. Metastasis can occur in various sites and is common in the liver. Classification of clinical stage is based upon guidelines. The local symptoms are like more common types of cancer. We could not make a differential diagnosis for the type 2 tumours in all five cases by endoscopic findings at the initial examination. We could not undertake surgical resection owing to their metastatic state, with two in liver, one in bone, and one in the distal lymph nodes at the time of diagnosis.