Giant Cell Arteritis Overlapping with Rheumatoid Arthritis and Sjögren’s Syndrome

GCA is an immune-mediated systemic vasculitis that mainly involves the large and middle arteries, especially the temporal arteries. GCA mainly occurs in people over the age of 50 years old. GCA tends to occur in western countries such as Europe, but rarely among blacks and Asians. Typical symptoms of GCA include headache, scalp tenderness, jaw claudication, visual impairment and inflammatory biomarkers such as ESR and CRP were significantly increased. Unilateral or bilateral vision loss is the most terrible complication of GCA. RA and SS are systemic autoimmune diseases, although GCA has been reported in patients with RA and SS respectively there have been no reports of linking the three diseases.